Untangling the double helix

Untangling the double helix

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Written by the man who discovered the first topoisomerase, this book covers the history of the DNA entanglement problem and explains how topoisomerases perform their magic in the cell and serve as therapeutic targets. Includes appendices and an index.Cells respond to such damage in diverse ways: Repair pathways are usually mobilized to repair DNA damage and restart ... cell-cycle progression during the S and/or G2 phase is often delayed to give a cell more time to resume and completeanbsp;...

Title:Untangling the double helix
Author: James C. Wang
Publisher:Cold Spring Harbor Laboratory Pr - 2009-06-15

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